Journal of Medicine and Applied Sciences

DOSIMETRIC EVALUATION OF THE IMPACT OF ACTIVE BREATHING CONTROL (ABC) SYSTEM ON PHYSICAL LUNG DOSE-VOLUME PARAMETERS IN PATIENTS RECEIVING CONSOLIDATIVE RADIATION THERAPY (RT) FOR EXTENSIVE STAGE SMALL CELL LUNG CANCER (ES-SCLC)

2023-11-25T01:46:30+03:00

Patients with extensive stage small cell lung cancer (ES-SCLC) suffer from impaired pulmonary functions due to their disease burden and avoidance of radiation therapy (RT) related pulmonary toxicity is of utmost importance. Within this context, efforts have been focused on improving the toxicity profile of radiation delivery by incorporating of contemporary RT techniques. Active Breathing Control (ABC) system has been developed for the management of respiratory motion in thoracoabdominal tumors by achieving reproducible breath holds. In this study, we evaluate the impact of the ABC system on physical lung dose-volume parameters (DVH) in patients receiving consolidative RT for ES-SCLC. For 16 patients referred to our clinic, two different RT plans with and without the ABC system were created and the mean lung dose (MLD) and V20 were analyzed. MLD and V20 were 2267 cGy and 36.7%, respectively at free breathing. MLD and V20 were 1882 cGy and 28.5%, respectively incorporation of the ABC system. The inclusion of the ABC system in consolidative thoracic RT therapy resulted in a 16.98% and 22.34% reduction in MLD and V20, respectively. For the radiotherapeutic management of ES-SCLC, the ABC system is considered to contribute to the treatment.

Comparison of Photon Interaction Parameters of Natural and Activated Malatya-Karababa Clay Minerals

2024-05-27T21:17:42+03:00

Clays are the oldest raw materials used since the beginning of human history. Pure clay is called kaolin and the color of the clay is white. The color of clay may change due to the influence of impurities in its structure. There are many types of clay and the colors of these clays can be pink, grey, red, green, black, blue or yellowish. Due to their specific processes, clays have a wide range of uses, including the production of ceramics and construction materials (such as sanitary ware and tiles), perfume production, and health care materials production. Kaolin is a type of clay obtained from granite rocks and preferred in making porcelain and ceramics. When a substance is exposed to ionizing radiation, it is important to determine some coefficients that characterize the interaction of radiation with this substance. In this study, μ_ρ Z_eff, N_elvalues of natural and activated Karababa clay were calculated and compared using the WinXCom computer program. Photon interaction parameters for natural and activated clay were examined and similar values were found. While μ_ρ, Z_eff and N_el had the highest values in the low energy region, the lowest values were obtained in the medium energy region. The results from this research can be used as a resource for shielding researchers as well as helping to develop new materials in radiation shielding.

Care of The Patient Monitored With The Diagnosis of Acute Coronary Syndrome According to The Uniterial Human Theory of Rogers: A Case Report

2024-05-08T19:40:27+03:00

Acute Coronary Syndrome has caused increases in morbidity and mortality worldwide. In this syndrome, which usually develops suddenly with complaints of chest pain and shortness of breath, most of the cases are caused by changeable lifestyle and manageable risk factors. Nurses have an important role in reducing these risk factors and in ensuring compliance with treatment. Rogers discussed the hemodynamic principles of reflection, coiling, and integration in his Unitary Human Theory. In the theory he developed, he evaluated the individual with its environmental and energy field. According to Rogers, these two fields interact and balance with each other. Health problems arise with the deterioration of this balance. Because of these health problems, nursing care is needed.. This case report was carried out to evaluate the patient with the principle of integrity by using Rogers' Unitary Human Theory in the care plan of a 44-year-old male patient who was admitted to the intensive care unit with a diagnosis of acute coronary syndrome. As a result of the study, it was seen that the care plan created according to Rogers' Unitary Human Theory was effective in making the necessary changes to improve the lifestyle of the patient diagnosed with Acute Coronary Syndrome.