Journal of Medicine and Applied Sciences

Ionizing electromagnetic radiation interaction properties of some antihypertensive drugs

2022-07-19T01:19:52+03:00

In the present work, the mass attenuation coefficient (MAC), half value layer (HVL), mean free path (mfp), effective atomic number (Z_eff), electron densities (N_el), exposure and absorption build-up factors (EBF and EABF) of six antihypertensive drugs (Fisonopril, Captopril, Losartan Potassium, Irbesartan, Ramipril, Telmisartan) have calculated using EpiXS program as a function of gamma-ray energy.

Losartan Potassium has larger MAC, Z_eff and N_el values and lower HVL and mfp values than the other studied drugs. The smallest EBF and EABF values are observed for Losartan Potassium for all of the penetration depths. As a result, it can be said that losartan absorbs more photon radiation than the other drugs.

Determining The Rate Of Normal Delivery, Miscarriage And Delivery Before Normal Time In Population of District Karak, Khyber Pakhtunkhwa, Pakistan

2022-04-13T13:17:05+03:00

Present study was conducted in district Karak to determine the rate of normal vaginal delivery, caesarian section delivery, miscarriage and delivery before time in district Karak. The study also aimed to determine the age dependent variations in these parameters in the population. Data was collected from district headquarter hospital, Karak and various clinics from 2015 to 2020. Data was distributed age wise also, linear regression was applied to determine year wise trend in the number of cases from 2015-2020. Percentage of normal delivery in 2015 was 63% which was reduced to 61 percent in 2020. Rate of caesarian section delivery in 2015 was 28% which increased to 30 % in 2020. However, percentage of miscarriage decreased from 6% to 5.5% from 2015 to 2020. Delivery before normal time was also increase from 2.8% to 3.26 percent in head quarter hospital, Karak. Percentage of normal delivery in 2015 was 70% which was reduced to 40 percent in 2020. Rate of caesarian section delivery in 2015 was 23% which increased to 40% in 2020. Similarly, percentage of miscarriage increased from 6% to 12% from 2015 to 2020. Delivery before normal time was also increase from 2.5% to 7.5 percent in clinics.Linear regression showed no significant difference in p value in different age groups except in the age group of 15 to 20 years age. Similarly, R2 value for delivery before time in20-30 years of age was also significantly high. No other groups showed significant R2 trend from 2015-2020. These results suggest that the risk factors related to this increase should be determined in pregnant women for normal healthy delivery. This early data provides basis for more studies to be done in district Karak in order to determine the factors associated with the rise in pregnancy loss and ceasarian section deliveries in district Karak.

The Importance Of Subcutaneus Tissue Thickness In Long Term Port Complications Skin Necrosis

2022-12-27T10:19:00+03:00

Santral venöz erişim için cilt altı tünelli venöz port yerleştirilen hastalarda, port yerleşim yerindeki cilt altı doku kalınlığının, cilt erozyonu gelişimi ile arasındaki ilişkiyi araştırmayı amaçladık. Nisan 2017 ile Ağustos 2017 tarihleri arasında kendi kliniğimizde venöz port yerleştirilen hastalarda cilt ile pektoral kas fasyası arasındaki doku kalınlığı B-mode ultrasonografi (US) ile affiniti G70 ultrason (Philips Ultrasound, Bothell, WA) cihazı ile 12L3 lineer prob kullanılarak ölçüldü. İşlem sonrası hastalar kendi kliniğimizde retrospektif olarak en az 6 ay olacak şekilde portu çıkarılana kadar veya hayatı sonlanana kadar takip edildi. Cilt altı doku kalınlığı 5mm’nin altında olan hastalar uzun dönem takip edilip cilt nekrozu gelişen hastalar tespit edildi. Çalışmaya dâhil edilen 36 hastanın 11’inde cilt ile pektoral kas fasyası arası doku kalınlığı 5 mm'nin altında bulundu. 2 hasta takip sürecinde ex olmuştur. 1 hasta başka merkezde tedavi gördüğünden takipten çıkarılmıştır. Takip ettiğimiz hastalardan sadece birinde cilt erozyonu gelişmiştir. Çalışmamızda elde ettiğimiz sonuçlar cilt erozyonunun sık görülmediğini göstermektedir. Cilt altı venöz port işlemi onkoloji hastalarında, düşük enfeksiyon riski ve konfor sağladığından doku kalınlığı 5 mm’den az olsa da bu şansın onlara verilmesi gerektiğini düşünüyoruz.

The tendency of brain tumor diseases in the world and the Republic of Uzbekistan

2022-08-02T13:16:03+03:00

According to GLOBOCAN for 2020, brain tumors (BTs) are the thirteenth in the list of most fatal cancers and twenty-first in the number of newly diagnosed Cancer cases in the world. The incidence of BTs is steadily increasing both worldwide and in the Republic of Uzbekistan. Thus, in 2020, in Uzbekistan, the BTs ranked 5th in the structure of general oncological morbidity and 4th among men and 6th among women. The purpose of the study: to conduct an oncoepidemiological assessment of global trends in brain tumors and the incidence of BTs in the Republic of Uzbekistan in 2019-2020. Global trends in morbidity and mortality from BTs show differences depending on territories and the level of economic development. The presence of features depending on gender was revealed: BTs occur more often in men, the ratio of diseased men and women is 1.1:0.9. The study of the oncoepidemiological situation of BTs in the Republic of Uzbekistan has shown that the incidence of BTs tends to increase. This determines the need for further studies of territorial differences and the search for factors of the occurrence of BTs.

Mechanical ileus due to a peritoneal band in a patient without a history of surgery

2022-09-22T16:51:53+03:00

This case report is aimed to present the diagnosis and treatment process of a patient who underwent laparotomy for ileus, and a peritoneal band was detected during laparotomy. A 65-year-old male patient was admitted to the emergency department with abdominal pain, nausea, and vomiting. He had no other disease or previous surgery. The patient had extensive tenderness and defence in the all-abdominal quadrants. Ampulla was empty on digital rectal examination. Multiple air-fluid levels were present on plain radiography. Computed tomography (CT) was planned for the patient for a detailed diagnosis. CT scan showed an approximately 40 mm diameter enlargement in the jejunal and ileal bowel loops. Despite the conservative treatment, the patient's abdominal physical examination worsened, so emergency surgery was planned for the patient. During laparotomy, enlargement was observed in all small bowel segments. It was observed that a single peritoneal band in the ileal intestinal part, approximately 100 mm proximal to the ileocecal valve, completely obstructed the small intestine lumen. Only bridectomy was performed, and the patient was discharged on the fifth postoperative day without complications.